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Reactivation of proliferin gene expression is associated with increased angiogenesis in a cell culture model of fibrosarcoma tumor progression

Proliferin (PLF) is an angiogenic placental hormone. We now report that PLF gene expression can also occur in a progressive fibrosarcoma mouse tumor cell model. PLF mRNA and protein are detectable at very low levels in cell lines derived from the mild noninvasive stage of tumor development. Expressi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Toft, Daniel J., Rosenberg, Suzanne B., Bergers, Gabriele, Volpert, Olga, Linzer, Daniel I. H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606769/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231364798
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