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Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

Chemotherapeutic drugs chronically administered to tumor-bearing mice, using a frequent schedule at doses substantially lower than the maximum tolerated dose (MTD) (i.e., metronomic dosing), can cause sustained and potent antiangiogenic effects by targeting the endothelial cells of newly growing tum...

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Bibliografiska uppgifter
Huvudupphovsmän: Bocci, Guido, Francia, Giulio, Man, Shan, Lawler, Jack, Kerbel, Robert S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC240719/
https://ncbi.nlm.nih.gov/pubmed/14561896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135406100
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