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Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
Chemotherapeutic drugs chronically administered to tumor-bearing mice, using a frequent schedule at doses substantially lower than the maximum tolerated dose (MTD) (i.e., metronomic dosing), can cause sustained and potent antiangiogenic effects by targeting the endothelial cells of newly growing tum...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC240719/ https://ncbi.nlm.nih.gov/pubmed/14561896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135406100 |
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