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Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

Chemotherapeutic drugs chronically administered to tumor-bearing mice, using a frequent schedule at doses substantially lower than the maximum tolerated dose (MTD) (i.e., metronomic dosing), can cause sustained and potent antiangiogenic effects by targeting the endothelial cells of newly growing tum...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Bocci, Guido, Francia, Giulio, Man, Shan, Lawler, Jack, Kerbel, Robert S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14561896/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2135406100
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