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A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

cAMP, the classical second messenger, regulates many diverse cellular functions. The primary effector of cAMP signals, protein kinase A, differentially phosphorylates hundreds of cellular targets. Little is known, however, about the spatial and temporal nature of cAMP signals and their information c...

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Detalhes bibliográficos
Main Authors: Rich, Thomas C., Fagan, Kent A., Tse, Tonia E., Schaack, Jerome, Cooper, Dermot M. F., Karpen, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60822/
https://ncbi.nlm.nih.gov/pubmed/11606735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221381398
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