Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice

BACKGROUND: Hormone sensitive lipase (HSL) is a neutral lipase that preferentially catalyzes the hydrolysis of diacylglycerol contributing to triacylglycerol breakdown in the adipose tissue. HSL has been implicated to play a role in tumor cachexia, a debilitating syndrome characterized by progressiv...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Xu, Mu, Chang, Hui-Hua, Jung, Xiaoman, Moro, Aune, Chou, Caroline Ei Ne, King, Jonathan, Hines, O. Joe, Sinnett-Smith, James, Rozengurt, Enrique, Eibl, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081906/
https://ncbi.nlm.nih.gov/pubmed/30086728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4713-y
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