Robust Early Inflammation of the Peri-pancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer

OBJECTIVES: Obesity increases the incidence of multiple types of cancer. Our previous work has shown that a high fat, high calorie diet (HFCD) leads to visceral obesity, pancreatic inflammation, and accelerated pancreatic neoplasia in KrasG12D (KC) mice. In this study we aimed to investigate the eff...

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Detalhes bibliográficos
Publicado no:Pancreas
Main Authors: Hertzer, Kathleen M., Xu, Mu, Moro, Aune, Dawson, David W., Du, Lin, Li, Gang, Chang, Hui-Hua, Stark, Alexander P., Jung, Xiaoman, Hines, O. Joe, Eibl, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854638/
https://ncbi.nlm.nih.gov/pubmed/26495779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000497
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