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Affinity Enrichment for MS: Improving the yield of low abundance biomarkers

INTRODUCTION: Mass spectrometry (MS) is the premier tool for discovering novel disease-associated protein biomarkers. Unfortunately, when applied to complex body fluid samples, MS has poor sensitivity for the detection of low abundance biomarkers (≪10 ng/mL), derived directly from the diseased tissu...

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Dades bibliogràfiques
Publicat a:Expert Rev Proteomics
Autors principals: Kim, Brianna, Araujo, Robyn, Howard, Marissa, Magni, Ruben, Liotta, Lance, Luchini, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081742/
https://ncbi.nlm.nih.gov/pubmed/29542338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14789450.2018.1450631
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