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Affinity Capture Enrichment versus Affinity Depletion: A Comparison of Strategies for Increasing Coverage of Low-Abundant Human Plasma Proteins

In the present study, we evaluated four small molecule affinity-based probes based on agarose-immobilized benzamidine (ABA), O-Phospho-L-Tyrosine (pTYR), 8-Amino-hexyl-cAMP (cAMP), or 8-Amino-hexyl-ATP (ATP) for their ability to remove high-abundant proteins such as serum albumin from plasma samples...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Palstrøm, Nicolai Bjødstrup, Rasmussen, Lars Melholt, Beck, Hans Christian
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460666/
https://ncbi.nlm.nih.gov/pubmed/32824511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165903
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