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p53 domains: suppression, transformation, and transactivation
We investigated the suppression, transformation, and transactivation functions of isolated segments of wild-type murine p53. Intact p53, but no segment of p53, inhibited cellular transformation by the activated ras and adenovirus E1A proteins. We conclude that most of p53 is needed for suppression o...
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| Опубликовано в: : | Gene Expr |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cognizant Communication Corporation
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081624/ https://ncbi.nlm.nih.gov/pubmed/8508031 |
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