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Kinetics of duplex formation for individual DNA strands within a single protein nanopore
A single oligonucleotide was covalently attached to a genetically engineered subunit of the heptameric protein pore, α-hemolysin, to allow DNA duplex formation inside the pore lumen. Single-channel current recording was used to study the properties of the modified pore. On addition of an oligonucleo...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60813/ https://ncbi.nlm.nih.gov/pubmed/11606775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231434698 |
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