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CRACR2A-mediated T cell receptor signaling promotes local effector Th1 and Th17 responses
CRAC channel regulator 2A (CRACR2A) is expressed abundantly in T cells and acts as a signal transmitter between T cell receptor stimulation and activation of the Ca(2+)-NFAT and JNK-AP1 pathways. CRACR2A has been linked to human diseases in numerous genome-wide association studies and was shown to b...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081249/ https://ncbi.nlm.nih.gov/pubmed/29987160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800659 |
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