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Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals
Oxidation of proteins by reactive oxygen species is associated with aging, oxidative stress, and many diseases. Although free and protein-bound methionine residues are particularly sensitive to oxidation to methionine sulfoxide derivatives, these oxidations are readily repaired by the action of meth...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60800/ https://ncbi.nlm.nih.gov/pubmed/11606777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231472998 |
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