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Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals

Oxidation of proteins by reactive oxygen species is associated with aging, oxidative stress, and many diseases. Although free and protein-bound methionine residues are particularly sensitive to oxidation to methionine sulfoxide derivatives, these oxidations are readily repaired by the action of meth...

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Detalhes bibliográficos
Main Authors: Moskovitz, Jackob, Bar-Noy, Shoshana, Williams, Wesley M., Requena, Jesus, Berlett, Barbara S., Stadtman, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60800/
https://ncbi.nlm.nih.gov/pubmed/11606777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231472998
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