Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress

The yeast peptide-methionine sulfoxide reductase (MsrA) was overexpressed in a Saccharomyces cerevisiae null mutant of msrA by using a high-copy plasmid harboring the msrA gene and its promoter. The resulting strain had about 25-fold higher MsrA activity than its parent strain. When exposed to eithe...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Moskovitz, Jackob, Flescher, Eliezer, Berlett, Barbara S., Azare, Janeen, Poston, J. Michael, Stadtman, Earl R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14071
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