Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress

The yeast peptide-methionine sulfoxide reductase (MsrA) was overexpressed in a Saccharomyces cerevisiae null mutant of msrA by using a high-copy plasmid harboring the msrA gene and its promoter. The resulting strain had about 25-fold higher MsrA activity than its parent strain. When exposed to eithe...

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Bibliografiset tiedot
Päätekijät: Moskovitz, Jackob, Flescher, Eliezer, Berlett, Barbara S., Azare, Janeen, Poston, J. Michael, Stadtman, Earl R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 1998
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC24328/
https://ncbi.nlm.nih.gov/pubmed/9826655
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