Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

In order to fully harness the potential of immunotherapy with chimeric antigen receptor (CAR)-modified T cells, pre-clinical studies must be conducted in immunocompetent animal models that closely mimic the immunosuppressive malignant glioma (MG) microenvironment. Thus, the goal of this project was...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Pituch, Katarzyna C., Miska, Jason, Krenciute, Giedre, Panek, Wojciech K., Li, Gina, Rodriguez-Cruz, Tania, Wu, Meijing, Han, Yu, Lesniak, Maciej S., Gottschalk, Stephen, Balyasnikova, Irina V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079480/
https://ncbi.nlm.nih.gov/pubmed/29503195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.001
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