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Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

The role of autophagy in cancer onset and progression appears still controversial. On one hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on the other hand, once internal energy resources are exhausted, it leads to cell death. In addition, autophagy interpheres...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Buccarelli, Mariachiara, Marconi, Matteo, Pacioni, Simone, De Pascalis, Ivana, D’Alessandris, Quintino Giorgio, Martini, Maurizio, Ascione, Barbara, Malorni, Walter, Larocca, Luigi Maria, Pallini, Roberto, Ricci-Vitiani, Lucia, Matarrese, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079099/
https://ncbi.nlm.nih.gov/pubmed/30082680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0864-7
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