Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

The role of autophagy in cancer onset and progression appears still controversial. On one hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on the other hand, once internal energy resources are exhausted, it leads to cell death. In addition, autophagy interpheres...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Buccarelli, Mariachiara, Marconi, Matteo, Pacioni, Simone, De Pascalis, Ivana, D’Alessandris, Quintino Giorgio, Martini, Maurizio, Ascione, Barbara, Malorni, Walter, Larocca, Luigi Maria, Pallini, Roberto, Ricci-Vitiani, Lucia, Matarrese, Paola
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079099/
https://ncbi.nlm.nih.gov/pubmed/30082680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0864-7
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