Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

The role of autophagy in cancer onset and progression appears still controversial. On one hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on the other hand, once internal energy resources are exhausted, it leads to cell death. In addition, autophagy interpheres...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Buccarelli, Mariachiara, Marconi, Matteo, Pacioni, Simone, De Pascalis, Ivana, D’Alessandris, Quintino Giorgio, Martini, Maurizio, Ascione, Barbara, Malorni, Walter, Larocca, Luigi Maria, Pallini, Roberto, Ricci-Vitiani, Lucia, Matarrese, Paola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079099/
https://ncbi.nlm.nih.gov/pubmed/30082680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0864-7
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