Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation In Vitro

The extremely poor prognosis of patients affected by glioblastoma (GBM, grade IV glioma) prompts the search for new and more effective therapies. In this regard, drug repurposing or repositioning can represent a safe, swift, and inexpensive way to bring novel pharmacological approaches from bench to...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Matteoni, Silvia, Matarrese, Paola, Ascione, Barbara, Buccarelli, Mariachiara, Ricci-Vitiani, Lucia, Pallini, Roberto, Villani, Veronica, Pace, Andrea, Paggi, Marco G., Abbruzzese, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952964/
https://ncbi.nlm.nih.gov/pubmed/33718225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.635472
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