Glioblastoma endothelium drives bevacizumab‐induced infiltrative growth via modulation of PLXDC1

Bevacizumab, a VEGF‐targeting monoclonal antibody, may trigger an infiltrative growth pattern in glioblastoma. We investigated this pattern using both a human specimen and rat models. In the human specimen, a substantial fraction of infiltrating tumor cells were located along perivascular spaces in...

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Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Falchetti, Maria Laura, D'Alessandris, Quintino Giorgio, Pacioni, Simone, Buccarelli, Mariachiara, Morgante, Liliana, Giannetti, Stefano, Lulli, Valentina, Martini, Maurizio, Larocca, Luigi Maria, Vakana, Eliza, Stancato, Louis, Ricci‐Vitiani, Lucia, Pallini, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Molecular Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590500/
https://ncbi.nlm.nih.gov/pubmed/30414187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31983
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