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Genetic and epigenetic influences on the loss of tolerance in autoimmunity
Immunological tolerance loss is fundamental to the development of autoimmunity; however, the underlying mechanisms remain elusive. Immune tolerance consists of central and peripheral tolerance. Central tolerance, which occurs in the thymus for T cells and bone marrow for B cells, is the primary way...
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| Pubblicato in: | Cell Mol Immunol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6079019/ https://ncbi.nlm.nih.gov/pubmed/29503444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.137 |
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