Enhancing T cell therapy through TCR signaling-responsive nanoparticle drug delivery

Adoptive cell therapy (ACT) with antigen-specific T cells has shown remarkable clinical success, but approaches to safely and effectively augment T cell function, especially in solid tumors, remain of great interest. Here we describe a strategy to “backpack” large quantities of supporting protein dr...

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Dettagli Bibliografici
Pubblicato in:Nat Biotechnol
Autori principali: Tang, Li, Zheng, Yiran, de Melo, Mariane Bandeira, Mabardi, Llian, Castaño, Ana P., Xie, Yu-Qing, Li, Na, Kudchodkar, Sagar B., Wong, Hing C., Jeng, Emily K., Maus, Marcela V., Irvine, Darrell J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078803/
https://ncbi.nlm.nih.gov/pubmed/29985479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4181
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