Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery

Although cytokine therapy is an attractive strategy to build a more robust immune response in tumors, cytokines have faced clinical failures due to toxicity. In particular, interleukin-12 has shown great clinical promise but was limited in translation due to systemic toxicity. In this study, we demo...

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Pubblicato in:ACS Nano
Autori principali: Barberio, Antonio E., Smith, Sean G, Correa, Santiago, Nguyen, Cathy, Nhan, Bang, Melo, Mariane, Tokatlian, Talar, Suh, Heikyung, Irvine, Darrell J., Hammond, Paula T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530125/
https://ncbi.nlm.nih.gov/pubmed/32692155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c03109
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