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Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation

Synapse maturation is a neural activity–dependent process during brain development, in which active synapses preferentially undergo maturation to establish efficient neural circuits in the brain. Defects in this process are implicated in various neuropsychiatric disorders. We have previously reporte...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Nagappan-Chettiar, Sivapratha, Johnson-Venkatesh, Erin M., Umemori, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078463/
https://ncbi.nlm.nih.gov/pubmed/29914984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001488
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