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Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation

Synapse maturation is a neural activity–dependent process during brain development, in which active synapses preferentially undergo maturation to establish efficient neural circuits in the brain. Defects in this process are implicated in various neuropsychiatric disorders. We have previously reporte...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nagappan-Chettiar, Sivapratha, Johnson-Venkatesh, Erin M., Umemori, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078463/
https://ncbi.nlm.nih.gov/pubmed/29914984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001488
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