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An Activity-Dependent Determinant of Synapse Elimination in the Mammalian Brain

To establish functional neural circuits in the brain, synaptic connections are refined by neural activity during development, where active connections are maintained while inactive ones are eliminated. However, the molecular signals that regulate synapse refinement remain to be elucidated. When we i...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Yasuda, Masahiro, Nagappan-Chettiar, Sivapratha, Johnson-Venkatesh, Erin M., Umemori, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068677/
https://ncbi.nlm.nih.gov/pubmed/33770504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.03.006
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