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Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation

Chronic neuroinflammation is a characteristic of Parkinson's disease (PD). Previous investigations have shown that Parkin gene mutations are related to the early-onset recessive form of PD and isolated juvenile-onset PD. Further, Parkin plays important roles in mitochondrial quality control and...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Xin, Di, Gu, Haiyan, Liu, Enping, Sun, Qinmiao
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078441/
https://ncbi.nlm.nih.gov/pubmed/29903906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001201
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