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SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis
Adult tongue epithelium is continuously renewed from epithelial progenitor cells, a process that requires hedgehog (HH) signaling. In mice, pharmacological inhibition of the HH pathway causes taste bud loss within a few weeks. Previously, we demonstrated that sonic hedgehog (SHH) overexpression in l...
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| 出版年: | Development |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078335/ https://ncbi.nlm.nih.gov/pubmed/29945863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.164889 |
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