TSPO–PET imaging using [(18)F]PBR06 is a potential translatable biomarker for treatment response in Huntington’s disease: preclinical evidence with the p75(NTR) ligand LM11A-31

Huntington’s disease (HD) is an inherited neurodegenerative disorder that has no cure. HD therapeutic development would benefit from a non-invasive translatable biomarker to track disease progression and treatment response. A potential biomarker is using positron emission tomography (PET) imaging wi...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Simmons, Danielle A, James, Michelle L, Belichenko, Nadia P, Semaan, Sarah, Condon, Christina, Kuan, Jason, Shuhendler, Adam J, Miao, Zheng, Chin, Frederick T, Longo, Frank M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077813/
https://ncbi.nlm.nih.gov/pubmed/29860333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy202
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