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Cancer Cell-Intrinsic PD-1 and Implications in Combinatorial Immunotherapy
Programmed death 1 (PD-1) and its two natural ligands PD-L1 and PD-L2 are responsible for delivering inhibitory signals that regulate the balance between T cell activation, tolerance, and immunopathology. In previous studies, PD-1 was found only expressed on the surface of immune cells, such as T ce...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077319/ https://ncbi.nlm.nih.gov/pubmed/30105035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01774 |
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