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PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations
Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulating T cell exhaustion. Binding of PD-1 to its ligand, programmed death-ligand 1 (PD-L1), activates downstream signaling pathways and inhibits T cell activation. Moreover abno...
Shranjeno v:
| izdano v: | Hum Vaccin Immunother |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605868/ https://ncbi.nlm.nih.gov/pubmed/30888929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1571892 |
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