Gene Expression Profiling of Primary Human Type I Alveolar Epithelial Cells Exposed to Bacillus anthracis Spores Reveals Induction of Neutrophil and Monocyte Chemokines

The lung is the entry site for Bacillus anthracis in inhalation anthrax, the most deadly form of the disease. Spores must escape through the alveolar epithelial cell (AEC) barrier and migrate to regional lymph nodes, germinate and enter the circulatory system to cause disease. Several mechanisms to...

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Veröffentlicht in:Microb Pathog
Hauptverfasser: Booth, J. Leland, Duggan, Elizabeth S., Patel, Vineet I., Wu, Wenxin, Burian, Dennis M., Hutchings, David C., White, Vicky L., Coggeshall, K. Mark, Dozmorov, Mikhail G., Metcalf, Jordan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077097/
https://ncbi.nlm.nih.gov/pubmed/29704667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2018.04.039
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