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Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen

BACKGROUND: Bacillus anthracis, the etiologic agent of anthrax, has recently been used as an agent of bioterrorism. The innate immune system initially appears to contain the pathogen at the site of entry. Because the human alveolar macrophage (HAM) plays a key role in lung innate immune responses, s...

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主要な著者: Dozmorov, Mikhail, Wu, Wenxin, Chakrabarty, Kaushik, Booth, J Leland, Hurst, Robert E, Coggeshall, K Mark, Metcalf, Jordan P
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752459/
https://ncbi.nlm.nih.gov/pubmed/19744333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-9-152
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