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Immunotherapy resistance by inflammation-induced dedifferentiation

A promising arsenal of targeted and immunotherapy treatments for metastatic melanoma has emerged over the last decade. With these therapies, we now face new mechanisms of tumor acquired resistance. We report here a patient whose metastatic melanoma underwent dedifferentiation as a resistance mechani...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Mehta, Arnav, Kim, Yeon Joo, Robert, Lidia, Tsoi, Jennifer, Comin-Anduix, Begoña, Berent-Maoz, Beata, Cochran, Alistair J., Economou, James S., Tumeh, Paul C., Puig-Saus, Cristina, Ribas, Antoni
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076867/
https://ncbi.nlm.nih.gov/pubmed/29899062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1178
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