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Immunotherapy resistance by inflammation-induced dedifferentiation

A promising arsenal of targeted and immunotherapy treatments for metastatic melanoma has emerged over the last decade. With these therapies, we now face new mechanisms of tumor acquired resistance. We report here a patient whose metastatic melanoma underwent dedifferentiation as a resistance mechani...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Mehta, Arnav, Kim, Yeon Joo, Robert, Lidia, Tsoi, Jennifer, Comin-Anduix, Begoña, Berent-Maoz, Beata, Cochran, Alistair J., Economou, James S., Tumeh, Paul C., Puig-Saus, Cristina, Ribas, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076867/
https://ncbi.nlm.nih.gov/pubmed/29899062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1178
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