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Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells

Replicative senescence hampers application of mesenchymal stromal cells (MSCs) because it limits culture expansion, impairs differentiation potential, and hinders reliable standardization of cell products. MSCs can be rejuvenated by reprogramming into induced pluripotent stem cells (iPSCs), which is...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Göbel, Carolin, Goetzke, Roman, Eggermann, Thomas, Wagner, Wolfgang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076311/
https://ncbi.nlm.nih.gov/pubmed/30076334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30069-6
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