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Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells
Replicative senescence hampers application of mesenchymal stromal cells (MSCs) because it limits culture expansion, impairs differentiation potential, and hinders reliable standardization of cell products. MSCs can be rejuvenated by reprogramming into induced pluripotent stem cells (iPSCs), which is...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076311/ https://ncbi.nlm.nih.gov/pubmed/30076334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30069-6 |
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