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Structure and nucleic acid binding properties of KOW domains 4 and 6–7 of human transcription elongation factor DSIF

The human transcription elongation factor DSIF is highly conserved throughout all kingdoms of life and plays multiple roles during transcription. DSIF is a heterodimer, consisting of Spt4 and Spt5 that interacts with RNA polymerase II (RNAP II). DSIF binds to the elongation complex and induces promo...

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Publicat a:Sci Rep
Autors principals: Zuber, Philipp K., Hahn, Lukas, Reinl, Anne, Schweimer, Kristian, Knauer, Stefan H., Gottesman, Max E., Rösch, Paul, Wöhrl, Birgitta M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076269/
https://ncbi.nlm.nih.gov/pubmed/30076330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30042-3
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