Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer’s disease (AD) pathology. We recently reported Aβ is an innate immune protein that protects against fungal and bacterial infections. Fibrilization pathways mediate Aβ antimicrobial activities. Thus, infection...

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Pubblicato in:Neuron
Autori principali: Eimer, William A., Vijaya Kumar, Deepak Kumar, Shanmugam, Nanda Kumar N., Rodriguez, Alex S., Mitchell, Teryn, Washicosky, Kevin J., György, Bence, Breakefield, Xandra O., Tanzi, Rudolph E., Moir, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075814/
https://ncbi.nlm.nih.gov/pubmed/30001512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.06.030
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