The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

BACKGROUND: The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. However, Aβ has been shown to be a specific ligand for a number of differe...

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Autori principali: Soscia, Stephanie J., Kirby, James E., Washicosky, Kevin J., Tucker, Stephanie M., Ingelsson, Martin, Hyman, Bradley, Burton, Mark A., Goldstein, Lee E., Duong, Scott, Tanzi, Rudolph E., Moir, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831066/
https://ncbi.nlm.nih.gov/pubmed/20209079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009505
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