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How does binding of agonist ligands control intrinsic molecular dynamics in human NMDA receptors?

NMDA-type glutamate receptors (NMDAR) are ligand-gated ion channels that contribute to excitatory neurotransmission in the central nervous system. NMDAR dysfunction has been found to be involved in various neurological disorders. Recent crystallographic and EM studies have shown the static structure...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Palmai, Zoltan, Houenoussi, Kimberley, Cohen-Kaminsky, Sylvia, Tchertanov, Luba
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075769/
https://ncbi.nlm.nih.gov/pubmed/30075003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201234
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