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How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5

Signal Transducer and Activator of Transcription STAT5 is a key mediator of cell proliferation, differentiation and survival. While STAT5 activity is tightly regulated in normal cells, its constitutive activation directly contributes to oncogenesis and is associated with a broad range of hematologic...

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發表在:PLoS One
Main Authors: Langenfeld, Florent, Guarracino, Yann, Arock, Michel, Trouvé, Alain, Tchertanov, Luba
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696835/
https://ncbi.nlm.nih.gov/pubmed/26717567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145142
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