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Nucleocytoplasmic Shuttling of Polypyrimidine Tract-binding Protein Is Uncoupled from RNA Export

Polypyrimidine tract binding protein, PTB/hnRNP I, is involved in pre-mRNA processing in the nucleus and RNA localization and translation in the cytoplasm. In this report, we demonstrate that PTB shuttles between the nucleus and cytoplasm in an energy-dependent manner. Deletion mutagenesis demonstra...

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Auteurs principaux: Kamath, Rajesh V., Leary, Daniel J., Huang, Sui
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC60757/
https://ncbi.nlm.nih.gov/pubmed/11739782
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