Nucleocytoplasmic Shuttling of Polypyrimidine Tract-binding Protein Is Uncoupled from RNA Export

Polypyrimidine tract binding protein, PTB/hnRNP I, is involved in pre-mRNA processing in the nucleus and RNA localization and translation in the cytoplasm. In this report, we demonstrate that PTB shuttles between the nucleus and cytoplasm in an energy-dependent manner. Deletion mutagenesis demonstra...

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Veröffentlicht in:	Mol Biol Cell
Hauptverfasser:	Kamath, Rajesh V., Leary, Daniel J., Huang, Sui
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60757/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.12.3808
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