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Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer’s disease

The objective of our study was to better understand the protective effects of the mitochondria-targeted tetra-peptide SS31 against amyloid beta (Aβ)-induced mitochondrial and synaptic toxicities in Alzheimer’s disease (AD) progression. Using intraperitoneal injections, we administered SS31 to an AD...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Reddy, P. Hemachandra, Manczak, Maria, Kandimalla, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075532/
https://ncbi.nlm.nih.gov/pubmed/28186562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx052
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