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POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer

Small cell lung cancer (SCLC) is widely considered to be a tumor of pulmonary neuroendocrine cells; however, a variant form of this disease has been described that lacks neuroendocrine features. Here, we applied domain-focused CRISPR screening to human cancer cell lines to identify the transcription...

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書目詳細資料
發表在:Genes Dev
Main Authors: Huang, Yu-Han, Klingbeil, Olaf, He, Xue-Yan, Wu, Xiaoli S., Arun, Gayatri, Lu, Bin, Somerville, Tim D.D., Milazzo, Joseph P., Wilkinson, John E., Demerdash, Osama E., Spector, David L., Egeblad, Mikala, Shi, Junwei, Vakoc, Christopher R.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075037/
https://ncbi.nlm.nih.gov/pubmed/29945888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.314815.118
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