IL-10 Receptor or TGF-β Neutralization Abrogates the Protective Effect of a Specific Nondigestible Oligosaccharide Mixture in Cow-Milk-Allergic Mice

BACKGROUND: Dietary nondigestible, short-chain galacto-, long-chain fructo-, and pectin-derived acidic oligosaccharides (GFAs) lower the effector response in cow-milk-allergic (CMA) mice; and forkhead box P3 (Foxp3)–positive regulatory T cells (Tregs) were shown to contribute to this. OBJECTIVE: The...

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Detalles Bibliográficos
Publicado en:J Nutr
Main Authors: Kerperien, JoAnn, Veening-Griffioen, Désirée, Wehkamp, Tjalling, van Esch, Betty C A M, Hofman, Gerard A, Cornelissen, Paquita, Boon, Louis, Jeurink, Prescilla V, Garssen, Johan, Knippels, Leon M J, Willemsen, Linette E M
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Nutritional Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074790/
https://ncbi.nlm.nih.gov/pubmed/29986071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxy104
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