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Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan
In aging cells, genomic instability is now recognized as a hallmark event. Throughout life, cells encounter multiple endogenous and exogenous DNA damaging events that are mostly repaired, but inevitably DNA mutations, chromosome rearrangements, and epigenetic deregulation begins to mount. Now that p...
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| 出版年: | Int J Mol Sci |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6073722/ https://ncbi.nlm.nih.gov/pubmed/29954095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071888 |
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