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Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan
In aging cells, genomic instability is now recognized as a hallmark event. Throughout life, cells encounter multiple endogenous and exogenous DNA damaging events that are mostly repaired, but inevitably DNA mutations, chromosome rearrangements, and epigenetic deregulation begins to mount. Now that p...
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| Publicado no: | Int J Mol Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6073722/ https://ncbi.nlm.nih.gov/pubmed/29954095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071888 |
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