The Anaphase Promoting Complex Regulates Yeast Lifespan and rDNA Stability by Targeting Fob1 for Degradation

Genomic stability, stress response, and nutrient signaling all play critical, evolutionarily conserved roles in lifespan determination. However, the molecular mechanisms coordinating these processes with longevity remain unresolved. Here we investigate the involvement of the yeast anaphase promoting...

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Bibliografiske detaljer
Main Authors: Menzel, Johannes, Malo, Mackenzie E., Chan, Cynthia, Prusinkiewicz, Martin, Arnason, Terra G., Harkness, Troy A. A.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2014
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948801/
https://ncbi.nlm.nih.gov/pubmed/24361936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158949
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