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Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus

Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological forms of tau are toxic and impair mitochondrial funct...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Jara, Claudia, Aránguiz, Alejandra, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072970/
https://ncbi.nlm.nih.gov/pubmed/30077079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.07.010
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